The Dow Jones Industrial Average opened higher on Wednesday as a post-earnings rally in shares of Microsoft Corp.
MSFT,
+3.85%

helped lift the blue-chip gauge while the S&P 500 and Nasdaq Composite sunk. The Dow gained 91 points, or 0.3%, at to trade at 33,218, according to FactSet data. Meanwhile, the S&P 500
SPX,
-0.97%

shed 22 points, or 0.5%, to 4,225, and the Nasdaq
COMP,
-1.37%

fell by 135 points, or 1.1%, to 13,000. The Dow had snapped a four-day losing streak on Tuesday as U.S. stocks rebounded following the worst stretch of the year.

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